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IRAK4-IN-28

Product Specifications

CAS Number

2952532-92-0

Target

IRAK

Related Pathways

NF-κB, Immunology/Inflammation

Bioactivity

IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a Kd of 0.58 nM for the target enzyme. It is utilized for research purposes in the study of inflammation and autoimmune diseases [1].

Smiles

C(NC=1N=C(C=CC1)C=2C=NN(C)C2)(=O)C3=C(N=C4C(=C3)OC(=N4)N5CCOCC5)N6CCN(CC6)C7CC7

Molecular Formula

C27H31N9O3

Molecular Weight

529.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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