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NSMase2-IN-1

Product Specifications

Target

Phospholipase

Related Pathways

Metabolism

Bioactivity

NSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with an IC50 value of 0.13 ± 0.06 μM, demonstrating metabolic stability in liver microsomes and a favorable brain-to-plasma ratio, indicating effective oral bioavailability. This compound is utilized in nervous system disease research [1].

Molecular Formula

C12H17N5O

Molecular Weight

247.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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