BI 7446
Product Specifications
CAS Number
2767011-00-5
Target
STING
Related Pathways
Immunology/Inflammation
Bioactivity
BI 7446 is a potent and selective cyclic dinucleotide (CDN) -based stimulator of interferon genes (STING) agonist capable of activating all five STING variants in cells, thus inducing tumor-specific immune-mediated tumor rejection. This compound is utilized in immuno-oncology research [1].
Smiles
OC1[C@@]2([C@@H](O[C@@]1(COP(=O)(S)O[C@@]3([C@@](COP(=O)(S)O2)(O[C@H]([C@@H]3F)N4C=5C(N=C4)=C(N)N=CN5)[H])[H])[H])N6C7=C(N=C6)C(=O)NN=C7)[H]
Molecular Formula
C20H22FN9O10P2S2
Molecular Weight
693.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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