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MK-8768

Product Specifications

CAS Number

1432729-22-0

Target

Others, GluR

Related Pathways

Others, Neuroscience

Bioactivity

MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized by excellent brain permeability.

Smiles

C(N)(=O)C=1C=C(C2=C(C=C(CN3C[C@H](C(F)(F)F)O[C@H](C)C3)C=C2)N1)C4=CN(C)N=C4

Molecular Formula

C21H22F3N5O2

Molecular Weight

433.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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