MK-8768
Product Specifications
CAS Number
1432729-22-0
Target
Others, GluR
Related Pathways
Others, Neuroscience
Bioactivity
MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized by excellent brain permeability.
Smiles
C(N)(=O)C=1C=C(C2=C(C=C(CN3C[C@H](C(F)(F)F)O[C@H](C)C3)C=C2)N1)C4=CN(C)N=C4
Molecular Formula
C21H22F3N5O2
Molecular Weight
433.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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