IR-251
Product Specifications
Target
Others|||Reactive Oxygen Species|||Mitochondrial Metabolism|||PPAR|||Wnt/beta-catenin
Related Pathways
NF-?B|||Others|||Cytoskeletal Signaling|||Metabolism|||Stem Cells|||DNA Damage/DNA Repair|||Immunology/Inflammation
Bioactivity
IR-251 is a mitochondrion-targeting near-infrared (NIR) fluorescent probe that selectively accumulates in tumor cell mitochondria through organic anion transporting polypeptides (OATPs), leading to mitochondrial dysfunction. By impeding peroxisome proliferator-activated receptor gamma (PPAR?), IR-251 promotes reactive oxygen species (ROS) overproduction, consequently inhibiting the ?-catenin signaling pathway as well as associated cell cycle and metastasis proteins. This mechanism contributes to the compound's ability to suppress tumor growth and metastasis [1].
Molecular Formula
C51H70BrClN4O2
Molecular Weight
886.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/123792164189634605/T79284
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
bs-18214R-PerCP 100 µL
Leishmania Major Surface Protease Polyclonal Antibody, PerCP Conjugated
Ask
View Details 
![ACSL3 Recombinant Mouse Monoclonal Antibody [A8F6-R]](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea811ed/imageurl/ha601213.webp)
41336151 3x1.0μg DNA
RPL30P13 CRISPR All-in-one AAV vector set (with saCas9)(Human)
Ask
View Details