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P-gp inhibitor 15

Product Specifications

Target

P-gp, Others

Related Pathways

Others, Neuroscience, Membrane transporter/Ion channel

Bioactivity

P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123 efflux. Additionally, this compound enhances the inhibitory effect of Paclitaxel on tumor progression in the KBV xenograft tumor model in nude mice [1].

Molecular Formula

C35H60N2O4

Molecular Weight

572.86

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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