P-gp inhibitor 15
Product Specifications
Target
P-gp, Others
Related Pathways
Others, Neuroscience, Membrane transporter/Ion channel
Bioactivity
P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123 efflux. Additionally, this compound enhances the inhibitory effect of Paclitaxel on tumor progression in the KBV xenograft tumor model in nude mice [1].
Molecular Formula
C35H60N2O4
Molecular Weight
572.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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