DPP-4-IN-8
Product Specifications
Target
Others, Proteasome, Interleukin, TNF
Related Pathways
Proteases/Proteasome, Apoptosis, Immunology/Inflammation, Others, Ubiquitination
Bioactivity
DPP-4-IN-8 (compound 27) is a potent and selective inhibitor of dipeptidyl peptidase 4 (DPP4), with an inhibition constant (Ki) of 0.96 μM. It inhibits the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells and dose-dependently reduces the expression of chemokines such as tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-1β (IL-1β) [1].
Molecular Formula
C16H12ClNO6
Molecular Weight
349.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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