Anticancer agent 127

Product Specifications

CAS Number

2410953-19-2

Target

IAP

Related Pathways

Apoptosis

Bioactivity

Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM, respectively, demonstrating anticancer effects [1].

Smiles

N(C(=O)[C@H]1N(C([C@@H](NC([C@@H](NC)C)=O)[C@@H]2CCCCC2)=O)CCC1)[C@H]3C=4C(=C(OS(F)(=O)=O)C=CC4)CC3

Molecular Formula

C26H37FN4O6S

Molecular Weight

552.66

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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