Anticancer agent 127
Product Specifications
CAS Number
2410953-19-2
Target
IAP
Related Pathways
Apoptosis
Bioactivity
Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM, respectively, demonstrating anticancer effects [1].
Smiles
N(C(=O)[C@H]1N(C([C@@H](NC([C@@H](NC)C)=O)[C@@H]2CCCCC2)=O)CCC1)[C@H]3C=4C(=C(OS(F)(=O)=O)C=CC4)CC3
Molecular Formula
C26H37FN4O6S
Molecular Weight
552.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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