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JAK-IN-30

Product Specifications

CAS Number

2891469-99-9

Target

JAK

Related Pathways

Chromatin/Epigenetic, Stem Cells, Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

Bioactivity

JAK-IN-30 (compound 31) is a water-soluble Janus kinase (JAK) inhibitor with IC50 values of 2 nM for JAK2, 15 nM for JAK1, 18 nM for JAK3, and 2 nM for TYK2, identified for its research potential in treating dry eye disease (DED) [1].

Smiles

C(C#N)C1(CN(C1)C2=NC(NC3=CC(C)=NS3)=NC=C2C)N4CCN(C)CC4

Molecular Formula

C19H26N8S

Molecular Weight

398.53

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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