RSV L-protein-IN-5
Product Specifications
CAS Number
851658-28-1
Target
RSV
Related Pathways
Microbiology/Virology
Bioactivity
RSV L-protein-IN-5 (Compound E) serves as a potent inhibitor of the Respiratory Syncytial Virus (RSV), with an EC50 value of 0.1 μM. It targets RSV polymerase with an IC50 of 0.66 μM and impedes RSV mRNA synthesis through the inhibition of transcript guanylation. The compound demonstrates moderate cytotoxicity, with a CC50 of 10.7 μM in HEp-2 cells, and effectively reduces viral titers in mouse models of RSV infection [1].
Smiles
O=C1C=2C3=C(N=C(N3)C=4N=C(C)C=CC4)C(N)=CC2C(C)(C)C(=O)N1CCCNCCC5=CC(OC)=C(OC)C=C5
Molecular Formula
C31H36N6O4
Molecular Weight
556.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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