PTD10
Product Specifications
CAS Number
2642231-19-2
Target
PROTACs, Apoptosis, BTK
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis, PROTAC
Purity
0.9912
Bioactivity
PTD10 is a BTK-targeting PROTAC degradator (DC50=0.5 nM, KD=2.28 nM) that induces apoptosis via caspase-dependent and mitochondrial pathways, suitable for studying B-cell dysregulation.
Smiles
O=C1C=2N(C3=C(C2)CC(C)(C)C3)CCN1C4=C(CO)C(=CC=N4)C=5C=C(NC6=CC=C(C=N6)N7[C@@H](C)CN(C(CNC8=C9C(C(=O)N(C9=O)C%10C(=O)NC(=O)CC%10)=CC=C8)=O)CC7)C(=O)N(C)C5
Molecular Formula
C49H51N11O8
Molecular Weight
922.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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