S-Gem
Product Specifications
CAS Number
2169925-98-6
Target
Autophagy, Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, Apoptosis, DNA Damage/DNA Repair, Autophagy
Bioactivity
S-Gem, a thioredoxin reductase (TrxR) -dependent prodrug of Gemcitabine, is selectively activated by TrxR. Studies indicate that S-Gem exhibits lower cytotoxicity than Gemcitabine [1].
Smiles
FC1(F)[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(NC(OC3CSSC3)=O)C=C2
Molecular Formula
C13H15F2N3O6S2
Molecular Weight
411.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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