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S-Gem

Product Specifications

CAS Number

2169925-98-6

Target

Autophagy, Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Related Pathways

Cell Cycle/Checkpoint, Apoptosis, DNA Damage/DNA Repair, Autophagy

Bioactivity

S-Gem, a thioredoxin reductase (TrxR) -dependent prodrug of Gemcitabine, is selectively activated by TrxR. Studies indicate that S-Gem exhibits lower cytotoxicity than Gemcitabine [1].

Smiles

FC1(F)[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(NC(OC3CSSC3)=O)C=C2

Molecular Formula

C13H15F2N3O6S2

Molecular Weight

411.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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