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DQn-1

Product Specifications

CAS Number

57343-54-1

Target

Others, Antibacterial

Related Pathways

Microbiology/Virology, Others

Bioactivity

DQn-1, a potent antifolate, demonstrates efficacy against Mycobacterium tuberculosis (Mtb) with an MIC 90 of 0.03 μM. It inhibits the DHFR enzyme, exhibiting IC 50 values of 8.7 nM for Mtb DHFR and 7.6 nM for the human counterpart [1].

Smiles

ClC=1C2=C(C=CC1CNC3=CC=C(C(O)=O)C=C3)N=C(N)N=C2N

Molecular Formula

C16H14ClN5O2

Molecular Weight

343.77

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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