DQn-1
Product Specifications
CAS Number
57343-54-1
Target
Others|||Antibacterial
Related Pathways
Microbiology/Virology|||Others
Bioactivity
DQn-1, a potent antifolate, demonstrates efficacy against Mycobacterium tuberculosis (Mtb) with an MIC 90 of 0.03 µM. It inhibits the DHFR enzyme, exhibiting IC 50 values of 8.7 nM for Mtb DHFR and 7.6 nM for the human counterpart [1].
Smiles
ClC=1C2=C(C=CC1CNC3=CC=C(C(O)=O)C=C3)N=C(N)N=C2N
Molecular Formula
C16H14ClN5O2
Molecular Weight
343.77
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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