FKBP51F67V-selective antagonist Ligand2
Product Specifications
CAS Number
1680228-76-5
Target
FKBP
Related Pathways
Immunology/Inflammation, Autophagy, Apoptosis
Bioactivity
FKBP51F67V-selective antagonist Ligand2 (example 3-3), a potent ligand, selectively binds to FKBP51 F67V variant without affinity for wild-type FKBP51 or FKBP52 [1], and effectively reverses the anxiogenic phenotype resulting from FKBP51 F67V overexpression in the amygdala.
Smiles
[C@H](C(=O)N1[C@H](C(O[C@H](CCC2=CC(OC)=C(OC)C=C2)C3=CC(OCCN4CCOCC4)=CC=C3)=O)CCCC1)(CC=C)C5=CC(OC)=C(OC)C(OC)=C5
Molecular Formula
C43H56N2O10
Molecular Weight
760.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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