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SOS1-IN-16

Product Specifications

CAS Number

2930763-85-0

Target

Cytochromes P450, Ras

Related Pathways

MAPK, GPCR/G Protein, Metabolism

Bioactivity

SOS1-IN-16 (Comp 54) is a selective SOS1 inhibitor with an IC50 of 7.2 nM and shows inhibitory activity against CYP3A4 with an IC50 of 8.9 μM using testosterone as a substrate. This compound is used in cancer research [1].

Smiles

N([C@H](C)C1=C(F)C(C(CO)(F)F)=CC=C1)C=2C3=C(C=CC(=C3)C4=CC(CC(N(C)C)=O)=C(OC)C=C4)N=C(C)N2

Molecular Formula

C30H31F3N4O3

Molecular Weight

552.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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