SOS1-IN-16
Product Specifications
CAS Number
2930763-85-0
Target
Cytochromes P450, Ras
Related Pathways
MAPK, GPCR/G Protein, Metabolism
Bioactivity
SOS1-IN-16 (Comp 54) is a selective SOS1 inhibitor with an IC50 of 7.2 nM and shows inhibitory activity against CYP3A4 with an IC50 of 8.9 μM using testosterone as a substrate. This compound is used in cancer research [1].
Smiles
N([C@H](C)C1=C(F)C(C(CO)(F)F)=CC=C1)C=2C3=C(C=CC(=C3)C4=CC(CC(N(C)C)=O)=C(OC)C=C4)N=C(C)N2
Molecular Formula
C30H31F3N4O3
Molecular Weight
552.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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