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PROTAC KRAS G12C degrader-3

Product Specifications

CAS Number

2768099-51-8

Target

Ras

Related Pathways

GPCR/G Protein, MAPK

Bioactivity

PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized in cancer research [1].

Smiles

C(NCC)(=O)C=1N(C(=NN1)C2=CC(C(C)C)=C(O)C=C2O)C3=CC=C(CN4CCC(C(=O)N5CCN(CC5)[C@H]6C[C@@H](COC7=NC(=C8C(=N7)CN(CC8)C=9C%10=C(C=CC9)C=CC=C%10Cl)N%11C[C@H](CC#N)N(C(C=C)=O)CC%11)N(C)C6)CC4)C=C3

Molecular Formula

C63H75ClN14O6

Molecular Weight

1159.81

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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