PROTAC KRAS G12C degrader-3
Product Specifications
CAS Number
2768099-51-8
Target
Ras
Related Pathways
GPCR/G Protein|||MAPK
Bioactivity
PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized in cancer research [1].
Smiles
C(NCC)(=O)C=1N(C(=NN1)C2=CC(C(C)C)=C(O)C=C2O)C3=CC=C(CN4CCC(C(=O)N5CCN(CC5)[C@H]6C[C@@H](COC7=NC(=C8C(=N7)CN(CC8)C=9C%10=C(C=CC9)C=CC=C%10Cl)N%11C[C@H](CC#N)N(C(C=C)=O)CC%11)N(C)C6)CC4)C=C3
Molecular Formula
C63H75ClN14O6
Molecular Weight
1159.81
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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