KRAS degrader-1

Product Specifications

CAS Number

2795275-59-9

Target

Kras|||PROTACs|||Others|||Ras

Related Pathways

GPCR/G Protein|||MAPK|||PROTAC|||Others

Bioactivity

KRAS degrader-1 (compound 1) is a potent agent that selectively targets KRAS proteins for degradation via the autophagy-lysosomal pathway [1].

Smiles

O(C[C@H]1N(CCCOCCOCCOCCOC2=C(Br)C=C(C=C3C=4C(NC3=O)=CC=C(I)C4)C=C2Br)CCC1)C5=NC(=C6C(CN(CC6)C=7C8=C(C=CC7)C=CC=C8Cl)=N5)N9C[C@H](CC#N)N(C(C(=C)F)=O)CC9

Molecular Formula

C55H57Br2ClFIN8O7

Molecular Weight

1283.25

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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