KRAS degrader-1
Product Specifications
CAS Number
2795275-59-9
Target
Kras|||PROTACs|||Others|||Ras
Related Pathways
GPCR/G Protein|||MAPK|||PROTAC|||Others
Bioactivity
KRAS degrader-1 (compound 1) is a potent agent that selectively targets KRAS proteins for degradation via the autophagy-lysosomal pathway [1].
Smiles
O(C[C@H]1N(CCCOCCOCCOCCOC2=C(Br)C=C(C=C3C=4C(NC3=O)=CC=C(I)C4)C=C2Br)CCC1)C5=NC(=C6C(CN(CC6)C=7C8=C(C=CC7)C=CC=C8Cl)=N5)N9C[C@H](CC#N)N(C(C(=C)F)=O)CC9
Molecular Formula
C55H57Br2ClFIN8O7
Molecular Weight
1283.25
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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