CK1-IN-2
Product Specifications
CAS Number
1383376-92-8
Target
P38 MAPK, Casein Kinase
Related Pathways
Metabolism, Stem Cells, MAPK
Purity
0.9931
Bioactivity
CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor with IC50 values of 123, 19.8, 26.8, and 74.3 nM for CK1a, CK1d, CK1e, and p38a, respectively, and is used in DUX4 overexpression-associated diseases, such as muscular dystrophy.
Smiles
O=C1OCC2=NC=CC(C3=CN(N=C3C=4C=CC(F)=CC4)C)=C12
Molecular Formula
C17H12FN3O2
Molecular Weight
309.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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