FEN1-IN-7
Product Specifications
CAS Number
824983-90-6
Target
FLAP
Related Pathways
Immunology/Inflammation
Bioactivity
FEN1-IN-7 (compound 16), a selective Flap endonuclease-1 (FEN1) inhibitor with an IC50 of 18 nM, plays a role in DNA damage repair in mammalian cells. Additionally, it targets the related endonuclease, xeroderma pigmentosum G (XPG), with an IC50 of 3.04 μM. FEN1-IN-7 enhances the sensitivity of cancer cells to potent DNA alkylating or methylating agents [1].
Smiles
C(N1C2=C(C(=O)N(O)C1=O)C(C)=CS2)C=3C=C4C(=C(OC)C3)OCO4
Molecular Formula
C16H14N2O6S
Molecular Weight
362.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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