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FEN1-IN-6

Product Specifications

CAS Number

824983-84-8

Target

FLAP

Related Pathways

Immunology/Inflammation

Bioactivity

FEN1-IN-6 (compound 9) is a potent Flap endonuclease-1 (FEN1, IC50 = 10 nM) inhibitor, crucial for DNA damage repair in mammalian cells, and also targets the related endonuclease xeroderma pigmentosum G (XPG) with an IC50 of 23 nM [1].

Smiles

S(=O)(=O)(C=1C2=C(SC1)C(=O)N(O)C(=O)N2)C3=CC=CC=C3

Molecular Formula

C12H8N2O5S2

Molecular Weight

324.33

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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