PF-07284892
Product Specifications
CAS Number
2498597-94-5
Target
Phosphatase, PERK
Related Pathways
Metabolism, Apoptosis
Purity
0.9777
Bioactivity
PF-07284892 (ARRY-558) is an orally active allosteric SHP2 inhibitor (IC50 = 21 nM) that reduces pERK expression and may be employed in solid tumour research.
Smiles
N[C@H]1C2(CC=3C1=CC=CC3)CCN(CC2)C=4N=CC(SC=5C(Cl)=C(N)N=CC5)=NN4
Molecular Formula
C21H22ClN7S
Molecular Weight
439.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K3139503 1.0 µg DNA
Gm15093 sgRNA CRISPR Lentivector (Mouse) (Target 2)
Sign In for Pricing
View Details 
BNC402273-100 1x 100 µL
Spermidine or Spermine N1-Acetyltransferase 1 (CPTC-SAT1-3), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details