PF-07284892
Product Specifications
CAS Number
2498597-94-5
Target
Phosphatase, PERK
Related Pathways
Metabolism, Apoptosis
Purity
0.9777
Bioactivity
PF-07284892 (ARRY-558) is an orally active allosteric SHP2 inhibitor (IC50 = 21 nM) that reduces pERK expression and may be employed in solid tumour research.
Smiles
N[C@H]1C2(CC=3C1=CC=CC3)CCN(CC2)C=4N=CC(SC=5C(Cl)=C(N)N=CC5)=NN4
Molecular Formula
C21H22ClN7S
Molecular Weight
439.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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