P2X3 antagonist 38
Product Specifications
CAS Number
2545974-71-6
Target
P2X Receptor
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Bioactivity
Compound 38, also known as Compound 4, is a potent, orally active P2X3 antagonist that demonstrates inhibitory activity with IC50 values of 0.132 μM, 0.165 μM, and 0.421 μM against human (hP2X3), rat (rP2X3), and guinea pig (gpP2X3) P2X3 receptors, respectively [1].
Smiles
N(C(OCC)=O)(C)[C@@H]1C(=NN(C(N[C@H](C)C=2C=NC(C(F)(F)F)=NC2)=O)C1)C3=CC=C(C)C=C3
Molecular Formula
C22H25F3N6O3
Molecular Weight
478.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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