P2X3 antagonist 38
Product Specifications
CAS Number
2545974-71-6
Target
P2X Receptor
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Bioactivity
Compound 38, also known as Compound 4, is a potent, orally active P2X3 antagonist that demonstrates inhibitory activity with IC50 values of 0.132 μM, 0.165 μM, and 0.421 μM against human (hP2X3), rat (rP2X3), and guinea pig (gpP2X3) P2X3 receptors, respectively [1].
Smiles
N(C(OCC)=O)(C)[C@@H]1C(=NN(C(N[C@H](C)C=2C=NC(C(F)(F)F)=NC2)=O)C1)C3=CC=C(C)C=C3
Molecular Formula
C22H25F3N6O3
Molecular Weight
478.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
AP11597PU-N 400 µL
Recoverin (RCVRN) (C-term) Rabbit Polyclonal Antibody
Sign In for Pricing
View Details 
BNC682153-100 1x 100 µL
TACSTD2 / TROP2 (Epithelial Marker) (TACSTD2/2153), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNCB2045-100 1x 100 µL
HSV1 (Herpes Simplex Virus Type I) ICP8 (HSVI/2045), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
17400-AAT 10 Reactions
ReadiLink™ iFluor® 488 Nick Translation dsDNA Labeling Kit
Sign In for Pricing
View Details 