PI3Kγ inhibitor 7
Product Specifications
CAS Number
2575863-25-9
Target
PI3K
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
PI3Kγ Inhibitor 7 (compound 2) is a potent, orally active agent that selectively inhibits PI3Kγ with an IC50 of 3.42 nM and demonstrates antitumor activity [1]. It also exhibits varying inhibitory effects on other PI3K isoforms, with IC50 values of 4768 nM for PI3Kα, 878.1 nM for PI3Kβ, and 355.2 nM for PI3Kδ.
Smiles
O=C1C=2C(N=C([C@@H](NC(=O)C3=C4N(N=C3N)C=CC=N4)C)N1C5=CC=CC=C5)=CC=CC2C#CC6=CN(N=C6)C7CC7
Molecular Formula
C31H25N9O2
Molecular Weight
555.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K1520905 3x 1.0 µg
OR5G1P sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
Sign In for Pricing
View Details 
207524-ML405 100 µL
CAPZB (F-actin-capping Protein Subunit beta, Capping Protein (actin filament) Muscle Z-line beta) CAPB, CAPPB, CAPZ, MGC104401, MGC129749, MGC129750 (MaxLight 405) discontinued
Sign In for Pricing
View Details 
T8666-35C 100 µg
TRPM2 (Transient Receptor Potential Cation Channel Subfamily M Member 2, Estrogen Responsive Element Associated Gene 1, Estrogen-responsive Element-associated Gene 1 Protein, EREG1, KNP3, Long Transient Receptor Potential Channel 2, LTRPC 2, LTRPC2, LTRPC-2, MGC133383, NUDT9H, NUDT9L1, Putative Ca2+ Channel Protein, Transient Receptor Potential Channel 7, TRPC 7, TRPC7)
Sign In for Pricing
View Details