PROTAC IRAK4 degrader-8
Product Specifications
CAS Number
2911615-06-8
Target
PROTACs|||IRAK
Related Pathways
PROTAC|||Immunology/Inflammation|||NF-?B
Bioactivity
PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 of 15.5 nM [1].
Smiles
C(=O)(N1CCC2(CC1)CCN(C[C@H]3CC[C@@H](CC3)N4C=C(NC(=O)C5=C6N(N=C5)C=CC(=N6)N7[C@@]8(C[C@](C7)(OC8)[H])[H])C(C(F)F)=N4)CC2)C9=CC(=C(Cl)C=C9)N%10C(=O)NC(=O)CC%10
Molecular Formula
C43H50ClF2N11O5
Molecular Weight
874.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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