MC-VC-PAB-Cyclohexanediamine-Thailanstatin A
Product Specifications
CAS Number
1609108-96-4
Target
Drug-Linker Conjugates for ADC|||DNA/RNA Synthesis
Related Pathways
Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint
Bioactivity
MC-VC-PAB-Cyclohexanediamine-Thailanstatin A, a spliceostatin analog and drug-linker conjugate for antibody-drug conjugates (ADC), comprises the cytotoxic component Thailanstatin A and the cleavable linker (MC-vc-PAB) . This compound is utilized in the synthesis of ADCs [1].
Smiles
O[C@H]1[C@]2(CO2)C[C@@H](CC(N[C@@H]3CC[C@@H](NC(OCC4=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN5C(=O)C=CC5=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C4)=O)CC3)=O)O[C@@H]1/C=C/C(=C/C[C@H]6[C@@H](C)C[C@@H](NC(/C=C\[C@@H](OC(C)=O)C)=O)[C@@H](C)O6)/C
Molecular Formula
C63H91N9O16
Molecular Weight
1230.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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