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TLR7/8 agonist 9

Product Specifications

CAS Number

2649170-17-0

Target

TLR, Others

Related Pathways

Immunology/Inflammation, Others

Bioactivity

TLR7/8 agonist 9 (Compound 25a), with EC50 values of 40 nM for hTLR7 and 23 nM for hTLR8, demonstrates anti-tumor properties and enhances the efficacy of PD-1/PD-L1 blockade treatments, making it valuable for cancer immunotherapy research [1].

Smiles

N(CCOC)C=1C2=C(C=CC(CC3=CC=C(CN(C)C)C=C3)=N2)N=C(N)N1

Molecular Formula

C20H26N6O

Molecular Weight

366.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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