TLR7/8 agonist 9
Product Specifications
CAS Number
2649170-17-0
Target
TLR|||Others
Related Pathways
Immunology/Inflammation|||Others
Bioactivity
TLR7/8 agonist 9 (Compound 25a), with EC50 values of 40 nM for hTLR7 and 23 nM for hTLR8, demonstrates anti-tumor properties and enhances the efficacy of PD-1/PD-L1 blockade treatments, making it valuable for cancer immunotherapy research [1].
Smiles
N(CCOC)C=1C2=C(C=CC(CC3=CC=C(CN(C)C)C=C3)=N2)N=C(N)N1
Molecular Formula
C20H26N6O
Molecular Weight
366.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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