ATR-IN-22
Product Specifications
CAS Number
2905312-07-2
Target
ATM/ATR
Related Pathways
DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling
Bioactivity
ATR-IN-22 (Compound 34), an orally active ATR inhibitor, exhibits potent anti-proliferative effects on MIAPaCa-2 cells with an IC50 value of less than 1 μM and demonstrates anti-tumor activity in colon cancer [1].
Smiles
C(#N)C1(C=2C3=C(C(=NC=C3)C=4C=CNN4)N=C(C2)N5[C@H](C)COCC5)CCC(N(C)C)CC1
Molecular Formula
C25H31N7O
Molecular Weight
445.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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