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Enpp-1-IN-17

Product Specifications

CAS Number

2289736-54-3

Target

Others, PDE

Related Pathways

Others, Metabolism

Bioactivity

Enpp-1-IN-17 (example 274) is a potent inhibitor of ENPP1, with inhibition constants (Ki values) ranging from 100 nM to 1 μM for cGAMP hydrolysis and greater than 1 μM for ATP hydrolysis, demonstrating a selectivity ratio of over 6.4 favoring cGAMP hydrolysis inhibition [1].

Smiles

O(C)C1=CC=2C(=NC=NC2C=C1OC)N3CCC4(CC3)CCNC4

Molecular Formula

C18H24N4O2

Molecular Weight

328.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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