Enpp-1-IN-17
Product Specifications
CAS Number
2289736-54-3
Target
Others|||PDE
Related Pathways
Others|||Metabolism
Bioactivity
Enpp-1-IN-17 (example 274) is a potent inhibitor of ENPP1, with inhibition constants (Ki values) ranging from 100 nM to 1 ?M for cGAMP hydrolysis and greater than 1 ?M for ATP hydrolysis, demonstrating a selectivity ratio of over 6.4 favoring cGAMP hydrolysis inhibition [1].
Smiles
O(C)C1=CC=2C(=NC=NC2C=C1OC)N3CCC4(CC3)CCNC4
Molecular Formula
C18H24N4O2
Molecular Weight
328.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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