GSK737
Product Specifications
CAS Number
2748687-95-6
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
GSK737 is a dual inhibitor of BRD4 BD1 and BD2, exhibiting pIC50 values of 5.3 and 7.3, respectively. It demonstrates low clearance, along with favorable solubility and permeability in rats [1].
Smiles
O([C@@H](C)C1=CC=CC=N1)C2=C(C=C(C(NC3CC3)=O)C=C2)C=4N=NN(C)C4
Molecular Formula
C20H21N5O2
Molecular Weight
363.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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