SLMP53-2
Product Specifications
CAS Number
1826116-38-4
Target
Apoptosis, Others, MDM-2/p53
Related Pathways
Apoptosis, Others
Bioactivity
SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction with Hsp70, thereby reinstating p53's transcriptional activity. This compound induces cell cycle arrest, apoptosis, and endoplasmic reticulum (ER) stress, displaying antitumor activity [1] [2].
Smiles
C([C@@H]1N2[C@@](C=3C(C2=O)=CC=CC3)(OC1)C4=CC=CC=C4)C=5C=6C(N(C)C5)=CC=CC6
Molecular Formula
C26H22N2O2
Molecular Weight
394.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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