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MDM2/XIAP-IN-2

Product Specifications

CAS Number

2761969-85-9

Target

Others, MDM-2/p53

Related Pathways

Others, Apoptosis

Bioactivity

MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP), promoting MDM2 degradation and impeding XIAP mRNA translation, thereby inhibiting cancer cell proliferation. It exhibits potent activity against the acute lymphoblastic leukemia cell line EU-1, with an IC50 of 0.3 μM [1].

Smiles

S(NC1=CC(C)=C(C)C=C1)(=O)(=O)C=2C=C3C4C(C(NC3=CC2)C5=CC=C(C(C(C)C)=O)C=C5)CCO4

Molecular Formula

C29H32N2O4S

Molecular Weight

504.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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