MDM2/XIAP-IN-2
Product Specifications
CAS Number
2761969-85-9
Target
Others, MDM-2/p53
Related Pathways
Others, Apoptosis
Bioactivity
MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP), promoting MDM2 degradation and impeding XIAP mRNA translation, thereby inhibiting cancer cell proliferation. It exhibits potent activity against the acute lymphoblastic leukemia cell line EU-1, with an IC50 of 0.3 μM [1].
Smiles
S(NC1=CC(C)=C(C)C=C1)(=O)(=O)C=2C=C3C4C(C(NC3=CC2)C5=CC=C(C(C(C)C)=O)C=C5)CCO4
Molecular Formula
C29H32N2O4S
Molecular Weight
504.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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