SA09-Cu
Product Specifications
CAS Number
155641-16-0
Target
Others, Antibacterial
Related Pathways
Others, Microbiology/Virology
Bioactivity
SA09-Cu is a potent, noncompetitive inhibitor of NDM-1, with an IC50 of 9.6 nM. It inactivates NDM-1 by oxidizing the enzyme's Zn (II) -thiolate site and resists reduction by bacterial intracellular thiols. SA09-Cu effectively restores Meropenem efficacy against various clinical NDM-1-producing carbapenem-resistant Enterobacteriaceae (CRE) and hampers the progression of carbapenem resistance [1].
Smiles
N(CCO)(C)C=1[S-][Cu+2]2([S-]C(N(CCO)C)=[S]2)[S]1
Molecular Formula
C8H16CuN2O2S4
Molecular Weight
364.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1263036-01 0.02 mg (E-Coli)
Recombinant African swine fever virus Structural protein p49 (Pret-087)
Sign In for Pricing
View Details MBS1263036-02 0.02 mg (Yeast)
Recombinant African swine fever virus Structural protein p49 (Pret-087)
Sign In for Pricing
View Details MBS1263036-03 0.1 mg (E-Coli)
Recombinant African swine fever virus Structural protein p49 (Pret-087)
Sign In for Pricing
View Details MBS1263036-04 0.1 mg (Yeast)
Recombinant African swine fever virus Structural protein p49 (Pret-087)
Sign In for Pricing
View Details MBS1263036-05 0.02 mg (Baculovirus)
Recombinant African swine fever virus Structural protein p49 (Pret-087)
Sign In for Pricing
View Details MBS1263036-06 0.02 mg (Mammalian-Cell)
Recombinant African swine fever virus Structural protein p49 (Pret-087)
Sign In for Pricing
View Details