Pim-1 kinase inhibitor 5

Product Specifications

CAS Number

2928606-67-9

Target

Pim

Related Pathways

Chromatin/Epigenetic|||JAK/STAT signaling

Bioactivity

Pim-1 kinase inhibitor 5 (Compound 4c) has an IC50 of 0.61 ?M and exhibits cytotoxicity against cancer cell lines HepG2, MCF-7, PC3, and HCT-116, with IC50 values ranging from 6.95 to 20.19 ?M [1].

Smiles

C(#N)C=1C(=CC(=NC1Cl)C2=CC=C(OC)C=C2)C3=CC4=C(N=C3Cl)C=CC=C4

Molecular Formula

C22H13Cl2N3O

Molecular Weight

406.26

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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