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PB131

Product Specifications

CAS Number

2924425-63-6

Target

HDAC

Related Pathways

Chromatin/Epigenetic|||DNA Damage/DNA Repair

Bioactivity

PB131, a selective and brain-permeable HDAC6 inhibitor, exhibits high binding affinity (IC50: 1.8 nM) and potent anti-inflammatory activity, making it suitable for inflammation research, particularly in neuroinflammation [1].

Smiles

C(N1C=2C(CCC1)=CC=CN2)C3=C(F)C=C(C(NO)=O)C=C3

Molecular Formula

C16H16FN3O2

Molecular Weight

301.32

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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