SIMR3030
Product Specifications
CAS Number
2708270-99-7
Target
SARS-CoV
Related Pathways
Microbiology/Virology
Bioactivity
SIMR3030, a potent inhibitor of SARS-CoV-2 PLpro, possesses an IC50 of 0.0399 μg/mL and demonstrates antiviral activity by diminishing the expression of SARS-CoV spike, ORF1b, IFN-α, and IL-6 mRNA. Additionally, SIMR3030 has been shown to have a satisfactory safety profile in mice [1].
Smiles
O(C)[C@]12[C@](N3[C@@](CC1)(C4=C(CC3)C=5C(N4)=CC=CC5)[H])(CC6=C(C2)C=7C(N6)=CC=C(OC)C7)[H]
Molecular Formula
C27H29N3O2
Molecular Weight
427.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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