HIV-1 protease-IN-8
Product Specifications
CAS Number
2925287-55-2
Target
HIV Protease
Related Pathways
Proteases/Proteasome|||Microbiology/Virology
Bioactivity
HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme with an IC50 of 0.32 nM. It exhibits IC50 values of 0.29 ?M for the wild-type HIV-1 (HIV-1 NL4-3) and 1.90 ?M against a drug-resistant variant (HIV-1 MDR), indicating strong antiviral activity against both strains [1].
Smiles
N(S(=O)(=O)C1=CC=C(O)C=C1)(C[C@H]([C@H](CC2=CC=CC=C2)NC(=O)[C@@H]3CCNC3)O)CC(C)C
Molecular Formula
C25H35N3O5S
Molecular Weight
489.63
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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