AM841
Product Specifications
CAS Number
871978-21-1
Target
Cannabinoid Receptor
Related Pathways
GPCR/G Protein
Bioactivity
AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor. It diminishes forskolin-stimulated cAMP accumulation and slows gastrointestinal motility [1] [2].
Smiles
OC1=C2[C@]3([C@](C(C)(C)OC2=CC(C(CCCCCCN=C=S)(C)C)=C1)(CC[C@@H](CO)C3)[H])[H]
Molecular Formula
C26H39NO3S
Molecular Weight
445.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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